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MAP & DIRECTIONS

Orangeburg County is strategically located between the state capital of Columbia and the port of Charleston. We invite you to enjoy our wonderful location and natural beauty that has much to offer!

Did you know Orangeburg County has access to 8 US Highways? US 21, US 78, US178, US 176, US 301, US 321 and US 601

Orangeburg County

Orangeburg County
Chamber of Commerce

155 Riverside Drive, SW
Orangeburg, SC 29116

FROM COLUMBIA

  • Take I-26 toward Charleston
  • Take Exit 145-A to Orangeburg which is US 601 & St. Matthews Road
  • It will change to Magnolia Street after coming into the city (approximately 5 miles)
  • After passing Claflin University & South Carolina University, turn right at the traffic light at McDonalds as US 601 joins US 301 (John C. Calhoun Drive)
  • Follow John C. Calhoun Drive for approximately 10 blocks
  • Turn right onto Riverside Drive at the sign for Edisto Memorial Gardens
  • The Chamber is the first building on the left

FROM CHARLESTON

  • Take I-26 W toward Columbia
  • Take Exit 154-A to Orangeburg which is US 301
  • Follow US 301 into the city (about 7-8 miles)
  • At the 9th traffic light turn right at Riverside Drive
  • The Chamber is located at the entrance of the Edisto Memorial Gardens

FROM I-95 NORTH AND I-95 SOUTH

  • Take I-26 W Exit 86B toward Columbia
  • Take Exit 154-A to Orangeburg
  • Follow Highway 301 into Orangeburg (about 7-8 miles)
  • Follow US 301 into the city (about 7-8 miles)
  • At the 9th traffic light turn right at Riverside Drive
  • The Chamber is located at the entrance of the Edisto Memorial Gardens

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